Deciphering the Rosetta Stone - Trans-Mitral Doppler Patterns for a Simplified Study of Left Ventricular Systolic Dysfunction

George Thomas

Abstract

Mini Review

Deciphering the Rosetta Stone - Trans-Mitral Doppler Patterns for a Simplified Study of Left Ventricular Systolic Dysfunction

George Thomas*

Published: 30 August, 2023 | Volume 7 - Issue 1 | Pages: 008-011

There is a renewed interest in heart failure treatments. With this, there is an increasing interest in heart failure with preserved ejection fraction. Trans-mitral Doppler is commonly used in the assessment of ‘diastolic’ function. It is fashionable to discuss diastolic dysfunction and diastology with the result that the more important systolic dysfunction has become passé. The current literature equates trans-mitral Doppler patterns to diastolic function when actually it is more relevant in systolic dysfunction. This article is an attempt to correct this flawed perception of trans-mitral Doppler.

Read Full Article HTML DOI: 10.29328/journal.ijcar.1001023 Cite this Article Read Full Article PDF

Keywords:
Trans-mitral Doppler; Diastolic dysfunction; Diastology; Systolic dysfunction; Systology

References

Murphy SP, Ibrahim NE, Januzzi JL Jr. Heart Failure With Reduced Ejection Fraction: A Review. JAMA. 2020 Aug 4;324(5):488-504. doi: 10.1001/jama.2020.10262. Erratum in: JAMA. 2020 Nov 24;324(20):2107. PMID: 32749493.
HEYER HE, HARRISON TR. The backward failure theory of congestive heart disease. Mod Concepts Cardiovasc Dis. 1947 Nov;16(11):1-4. PMID: 18856413.
Nagueh SF. Diastology: 2020-A practical guide. Echocardiography. 2020 Nov;37(11):1919-1925. doi: 10.1111/echo.14742. Epub 2020 Jun 1. PMID: 32476157.
Vasan RS, Xanthakis V, Lyass A, Andersson C, Tsao C, Cheng S, Aragam J, Benjamin EJ, Larson MG. Epidemiology of Left Ventricular Systolic Dysfunction and Heart Failure in the Framingham Study: An Echocardiographic Study Over 3 Decades. JACC Cardiovasc Imaging. 2018 Jan;11(1):1-11. doi: 10.1016/j.jcmg.2017.08.007. Epub 2017 Oct 5. PMID: 28917679; PMCID: PMC5756128.
Chengode S. Left ventricular global systolic function assessment by echocardiography. Ann Card Anaesth. 2016 Oct;19(Supplement):S26-S34. doi: 10.4103/0971-9784.192617. PMID: 27762246; PMCID: PMC5100240.
Thomas G. A simplified study of trans-mitral Doppler patterns. Cardiovasc Ultrasound. 2008 Nov 28;6:59. doi: 10.1186/1476-7120-6-59. PMID: 19040751; PMCID: PMC2607254.
Lester SJ, Tajik AJ, Nishimura RA, Oh JK, Khandheria BK, Seward JB. Unlocking the mysteries of diastolic function: deciphering the Rosetta Stone 10 years later. J Am Coll Cardiol. 2008 Feb 19;51(7):679-89. doi: 10.1016/j.jacc.2007.09.061. PMID: 18279730.
Nagueh SF, Smiseth OA, Appleton CP, Byrd BF 3rd, Dokainish H, Edvardsen T, Flachskampf FA, Gillebert TC, Klein AL, Lancellotti P, Marino P, Oh JK, Popescu BA, Waggoner AD. Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2016 Apr;29(4):277-314. doi: 10.1016/j.echo.2016.01.011. PMID: 27037982.
Silbiger JJ. Pathophysiology and Echocardiographic Diagnosis of Left Ventricular Diastolic Dysfunction. J Am Soc Echocardiogr. 2019 Feb;32(2):216-232.e2. doi: 10.1016/j.echo.2018.11.011. PMID: 30717860.
Palatini P, Frigo G, Vriz O, Bertolo O, Dal Follo M, Daniele L, Visentin P, Pessina AC; HARVEST Study Group. Early signs of cardiac involvement in hypertension. Am Heart J. 2001 Dec;142(6):1016-23. doi: 10.1067/mhj.2001.119378. PMID: 11717606.
Lewis BS. Doppler diastolic transmitral ventricular filling patterns--towards a better understanding. Eur Heart J. 1996 Apr;17(4):493-5. doi: 10.1093/oxfordjournals.eurheartj.a014897. PMID: 8733077.
Stoddard MF, Labovitz AJ, Pearson AC. The role of Doppler echocardiography in the assessment of left ventricular diastolic function. Echocardiography. 1992 Jul;9(4):387-406. doi: 10.1111/j.1540-8175.1992.tb00483.x. PMID: 10147786.
Araujo AQ, Araujo AQ. Elucidating the B bump on the mitral valve M-mode echogram in patients with severe left ventricular systolic dysfunction. Int J Cardiol. 2004 May;95(1):7-12. doi: 10.1016/j.ijcard.2003.02.003. PMID: 15159031.
Previtali M, Chieffo E, Ferrario M, Klersy C. Echocardiographic evaluation of left ventricular diastolic function: correlation between echocardiographic and hemodynamic parameters. Minerva Cardioangiol. 2007 Dec;55(6):733-40. PMID: 18091642.
Yamada H, Goh PP, Sun JP, Odabashian J, Garcia MJ, Thomas JD, Klein AL. Prevalence of left ventricular diastolic dysfunction by Doppler echocardiography: clinical application of the Canadian consensus guidelines. J Am Soc Echocardiogr. 2002 Oct;15(10 Pt 2):1238-44. doi: 10.1067/mje.2002.124877. PMID: 12411911.
Cikes M, Solomon SD. Beyond ejection fraction: an integrative approach for assessment of cardiac structure and function in heart failure. Eur Heart J. 2016 Jun 1;37(21):1642-50. doi: 10.1093/eurheartj/ehv510. Epub 2015 Sep 28. PMID: 26417058.
Unlüer EE, Karagöz A, Akoğlu H, Bayata S. Visual estimation of bedside echocardiographic ejection fraction by emergency physicians. West J Emerg Med. 2014 Mar;15(2):221-6. doi: 10.5811/westjem.2013.9.16185. PMID: 24672616; PMCID: PMC3966449.
Barry T, Farina JM, Chao CJ, Ayoub C, Jeong J, Patel BN, Banerjee I, Arsanjani R. The Role of Artificial Intelligence in Echocardiography. J Imaging. 2023 Feb 20;9(2):50. doi: 10.3390/jimaging9020050. PMID: 36826969; PMCID: PMC9962859.
Thomas G. Classification of transmitral Doppler patterns. Indian Heart J. 2005 May-Jun;57(3):275-6. PMID: 16196192.
Nishimura RA, Tajik AJ. Evaluation of diastolic filling of left ventricle in health and disease: Doppler echocardiography is the clinician's Rosetta Stone. J Am Coll Cardiol. 1997 Jul;30(1):8-18. doi: 10.1016/s0735-1097(97)00144-7. PMID: 9207615.
Saha SK, Kiotsekoglou A, Nanda NC. Echocardiography 2020: Toward deciphering the "Rosetta stone" of left ventricular diastolic function. Echocardiography. 2020 Nov;37(11):1886-1889. doi: 10.1111/echo.14830. PMID: 33283344.

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